With siera, users ingest Analysis Results Standard (ARS) metadata and auto-generate R scripts that, when run with corresponding ADaM datasets, provide Analysis Results Datasets (ARDs).
The CDISC Analysis Results Standard is a foundational standard that facilitates automation, reproducibility, reusability and traceability of analysis results data.
ARS metadata is officially represented using JSON format (though there is also an Excel representation for easier readability, but the JSON format is recommended for official ARS usage). Such a JSON file contains all relevant metadata to be able to calculate the Analysis Results for a specific Reporting Event. This metadata includes (but is not limited to):
Applying all these concepts to ADaM input data, yields Analysis Results in Dataset format (ARDs).
siera
can be installed from CRAN with:
install.packages("siera")
#> package 'siera' successfully unpacked and MD5 sums checked
#>
#> The downloaded binary packages are in
#> C:\Users\mbosm\AppData\Local\Temp\RtmpEFtLhb\downloaded_packages
The development version can be installed from Github using
::install_github("clymbclinical/siera") devtools
The siera
package has one main function, called
readARS
. This function takes ARS metadata as input (either
JSON or xlsx format), and makes use of the various metadata pieces to
populate R scripts, which an be run as-is to produce ARDs. One R script
is created for each output (table) as defined in the ARS metadata for
the reportingg event.
In order to make use of this function, the following are required as arguments:
See the Getting Started vignette for examples and more detail on the process.