mtdesign: Mander and Thompson Designs

Implements Mander & Thompson's (2010) <doi:10.1016/j.cct.2010.07.008> methods for two-stage designs optimal under the alternative hypothesis for phase II [cancer] trials. Also provides an implementation of Simon's (1989) <doi:10.1016/0197-2456(89)90015-9> original methodology and allows exploration of the operating characteristics of sub-optimal designs.

Version:	0.1.3
Imports:	dplyr, futile.logger, ggplot2, magrittr, methods, Rcpp, rlang, tibble, tidyr
LinkingTo:	Rcpp, BH
Suggests:	parallel, testthat (≥ 3.0.0), withr
Published:	2025-08-23
DOI:	10.32614/CRAN.package.mtdesign
Author:	John Kirkpatrick [aut, cre]
Maintainer:	John Kirkpatrick <mtdesign at puzzledface.net>
BugReports:	https://github.com/openpharma/mtdesign/issues
License:	GPL (≥ 3)
URL:	https://github.com/openpharma/mtdesign
NeedsCompilation:	yes
Language:	en-GB
Materials:	README, NEWS
CRAN checks:	mtdesign results

Documentation:

Reference manual:

mtdesign.html , mtdesign.pdf

Downloads:

Package source:	mtdesign_0.1.3.tar.gz
Windows binaries:	r-devel: mtdesign_0.1.3.zip, r-release: mtdesign_0.1.3.zip, r-oldrel: mtdesign_0.1.3.zip
macOS binaries:	r-release (arm64): mtdesign_0.1.3.tgz, r-oldrel (arm64): mtdesign_0.1.3.tgz, r-release (x86_64): mtdesign_0.1.3.tgz, r-oldrel (x86_64): mtdesign_0.1.3.tgz
Old sources:	mtdesign archive

Linking:

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