Package: upndown
Type: Package
Title: Utilities and Design Aids for Up-and-Down Dose-Finding Studies
Version: 1.0.0
Date: 2026-11-10
Description: Up-and-Down (UD) is the most popular design approach to dose-finding, but it has been severely under-served by the statistical and computing communities. This is the first package that comprehensively addresses UD's needs. Development version available on Github: assaforon/upndown. Recent applied UD tutorial: Oron et al., 2022 <doi:10.1097/ALN.0000000000004282>. Recent methodological overview: Oron and Flournoy, 2025 <doi:10.51387/24-NEJSDS74>.
License: GPL-2
Authors@R: 
    person('Assaf P.','Oron', role=c('cre','aut'), email='assaf.oron@gmail.com')
Encoding: UTF-8
Suggests: knitr, rmarkdown
Imports: cir, expm, MASS, plyr
VignetteBuilder: knitr
Config/roxygen2/version: 8.1.1
NeedsCompilation: no
Packaged: 2026-11-10 15:33:13 UTC; assaf
Author: Assaf P. Oron [cre, aut]
Maintainer: Assaf P. Oron <assaf.oron@gmail.com>
Repository: CRAN
Date/Publication: 2026-11-13 09:10:02 UTC
Built: R 4.5.3; ; 2026-11-14 00:53:28 UTC; windows
