Metric	Day 1 N = 2001	Day 7 N = 2001
AUC (ng/mL*h)	134 (102–168)	199 (131–297)
Cmax (ng/mL)	10.2 (7.8–13.1)	14.8 (10.4–20.6)
tmax (h)	2.00 (1.00–6.00)	2.00 (1.00–6.00)
Ctrough (ng/mL)	2.89 (1.43–4.50)	4.18 (1.99–8.75)
1 Median (5% Centile–95% Centile)